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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KSR2
All Species:
7.88
Human Site:
S196
Identified Species:
17.33
UniProt:
Q6VAB6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VAB6
NP_775869.3
950
107632
S196
P
W
I
R
T
H
L
S
Q
S
P
R
V
P
S
Chimpanzee
Pan troglodytes
XP_001145739
986
111275
S172
P
W
I
R
T
H
L
S
Q
S
P
R
V
P
S
Rhesus Macaque
Macaca mulatta
XP_001083311
805
90894
T120
A
V
R
T
P
P
R
T
P
N
I
V
T
T
V
Dog
Lupus familis
XP_853953
898
99758
R190
W
S
S
L
D
A
R
R
E
S
G
S
G
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVC0
959
108554
Q197
W
I
R
T
H
L
S
Q
S
P
R
V
Q
T
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514916
259
29171
Chicken
Gallus gallus
Q04982
806
89347
A121
S
A
S
T
D
T
V
A
S
S
S
S
S
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137513
942
106704
L194
S
Q
W
V
R
L
Q
L
S
Q
S
P
K
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11346
782
88616
T97
S
R
L
W
F
L
P
T
E
Y
Q
E
L
T
S
Honey Bee
Apis mellifera
XP_393005
895
100160
T170
W
D
R
H
H
L
R
T
G
A
S
P
R
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
F136
D
D
G
F
R
L
G
F
G
G
G
G
G
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
84.3
51
N.A.
95.5
N.A.
N.A.
25.1
24.3
N.A.
82.3
N.A.
24.9
36.4
N.A.
N.A.
Protein Similarity:
100
92.1
84.5
64.6
N.A.
97
N.A.
N.A.
26.3
40.2
N.A.
90.1
N.A.
40.9
53.5
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
0
N.A.
N.A.
0
6.6
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
0
N.A.
N.A.
0
20
N.A.
0
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
0
10
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
0
0
19
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
19
0
0
10
0
0
0
% E
% Phe:
0
0
0
10
10
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
19
10
19
10
19
0
0
% G
% His:
0
0
0
10
19
19
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
19
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% K
% Leu:
0
0
10
10
0
46
19
10
0
0
0
0
10
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
19
0
0
0
10
10
10
0
10
10
19
19
0
28
0
% P
% Gln:
0
10
0
0
0
0
10
10
19
10
10
0
10
0
0
% Q
% Arg:
0
10
28
19
19
0
28
10
0
0
10
19
10
0
0
% R
% Ser:
28
10
19
0
0
0
10
19
28
37
28
19
10
19
37
% S
% Thr:
0
0
0
28
19
10
0
28
0
0
0
0
10
28
0
% T
% Val:
0
10
0
10
0
0
10
0
0
0
0
19
19
0
10
% V
% Trp:
28
19
10
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _